Training School 1

This postgraduate training school, organized as part of the Horizon Europe VITAL consortium, aims to equip participants with cutting-edge skills and knowledge in multi-scale and multi-organ modeling for personalized healthcare applications. The training will focus on computational methods that support the development of a virtual human twin for optimizing medical and surgical therapies in circulation overload disorders (CODs).

The lectures will cover core topics in systems modeling, including bond graph modeling, multiscale modeling, and 0D and 1D circulation modeling. Participants will explore advanced high-fidelity 3D organ modeling techniques, along with practical approaches for uncertainty quantification, sensitivity analysis, and Bayesian inference. Surrogate modeling will also be discussed as a tool for accelerating computational workflows in clinical applications.

Throughout the course, participants will engage with theory, simulation, and real-world case studies, with a focus on integrating data from wearable technology and clinical environments. The training school aims to foster interdisciplinary collaboration and prepare attendees to leverage computational models for individualized, sex-specific treatment strategies.